Front publications - GMGM - Génétique moléculaire, génomique, microbiologie

24 September 2024

New publication : Monitoring mitochondrial localization of dual localized proteins using a Bi-Genomic Mitochondrial-Split-GFP

Autors : Solène Zuttion, Bruno Senger, Chiranjit Panja, Sylvie Friant, Róża Kucharczyk and Hubert Dominique Becker Photo : ©Jaime-Olivares

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Équipe Tarassov-Smirnov

10 June 2024

New publication in Nature Cell Biology by the MITO team in collaboration with the University of Liège

Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma. doi.org/10.1038/s41556-024-01439-2 Transfer RNA dynamics contribute to cancer development through regulation of codon-specific messenger RNA translation. Specific aminoacyl-tRNA synthetases can either promote or suppress…

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Équipe Schacherer

30 May 2024

New publication in collaboration

Natural proteome diversity links aneuploidy tolerance to protein turnover. Julia Muenzner, Pauline Trébulle, Federica Agostini, Henrik Zauber, Christoph B. Messner, Martin Steger, Christiane Kilian, Kate Lau, Natalie Barthel, Andrea Lehmann, Kathrin Textoris-Taube, Elodie Caudal, Anna-Sophia Egger,…

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Équipe Schacherer

30 May 2024

New publication in Nature Genetics

Pan-transcriptome reveals a large accessory genome contribution to gene expression variation in yeast. Élodie Caudal, Victor Loegler, Fabien Dutreux, Nikolaos Vakirlis, Élie Teyssonnière, Claudia Caradec, Anne Friedrich, Jing Hou, Joseph Schacherer. Nature Genetics. 2024. doi:…

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Équipe Schacherer

6 May 2024

New publication in PNAS

Species-wide quantitative transcriptomes and proteomes reveal distinct genetic control of gene expression variation in yeast. Elie M Teyssonnière, Pauline Trébulle, Julia Muenzner, Joseph Schacherer. PNAS. 2024. doi:10.1073/pnas.2319211121 Gene expression varies between individuals and corresponds…

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Équipe Schacherer

15 March 2024

New publication in collaboration

Absence of chromosome axis protein recruitment prevents meiotic recombination chromosome-wide in the budding yeast Lachancea kluyveri. Sylvain Legrand, Asma Saifudeen, Hélène Bordelet, Julien Vernerey, Arnaud Guille, Amaury Bignaud, Agnès Thierry, Laurent Acquaviva, Maxime Gaudin, Aurore Sanchez,…

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Équipe Schacherer

16 February 2024

New publication of the team

Diallel panel reveals a significant impact of low-frequency genetic variants on gene expression variation in yeast. Andreas Tsouris, Gauthier Brach, Anne Friedrich, Jing Hou, Joseph Schacherer. Mol Syst Biol. 2024. doi:10.1038/s44320-024-00021-0 Unraveling the genetic sources of gene expression…

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Équipe Schacherer

30 January 2024

New publication in NAR

Translation variation across genetic backgrounds reveals a post-transcriptional buffering signature in yeast. Elie M Teyssonniere, Yuichi Shichino, Mari Mito, Anne Friedrich, Shintaro Iwasaki, Joseph Schacherer. Nucleic Acids Research. 2024. doi:10.1093/nar/gkae030 Gene expression is known to…

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Équipe Schacherer

15 January 2024

New publication in Cell Genomics

Non-additive genetic components contribute significantly to population-wide gene expression variation. Andreas Tsouris, Gauthier Brach, Joseph Schacherer, Jing Hou. Gene expression variation, an essential step between genotype and phenotype, is collectively controlled by local (cis) and distant (tr…

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Équipe Tarassov-Smirnov

15 September 2023

New publication by MITO-team

Targeting of CRISPR-Cas12a crRNAs into human mitochondria