The MITO team created an innovative subcellular transcriptomics approach, CoLoC-seq - Nucleic Acids Research
A new genome-wide method that marries classical enzymatic kinetics, deep sequencing, and mathematical modelling - CoLoC-seq - has been created in the MITO team and successfully applied to human mitochondria to tell resident RNAs from contaminants.
MITO team : editorial in Frontiers Physiology
Editorial for a special issue of Frontiers Physiology
New publication of the MITO team in Computational and Structural Biotechnology Journal
Theoretical and mathematical biology paper about hub-centred RNA-protein networks
New publication in Molecular Biology and Evolution
Loss of heterozygosity spectrum depends on ploidy level in natural yeast populations. Abhishek Dutta, Fabien Dutreux, Joseph Schacherer. Molecular Biology and Evolution. 2022. doi:10.1093/molbev/msac214 The appearance of genomic variations such as loss of heterozygosity (LOH) has a significant…
New publication in PNAS
Loss-of-function mutation survey revealed that genes with background-dependent fitness are rare and functionally related in yeast. Elodie Caudal, Anne Friedrich, Arthur Jallet, Marion Garin, Jing Hou, Joseph Schacherer. Proc Natl Acad Sci U S A. 2022. doi:10.1073/pnas.2204206119 In natural…
New publication
Extensive simulations assess the performance of genome-wide association mapping in various Saccharomyces cerevisiae subpopulations. Jackson Peter, Anne Friedrich, Gianni Liti, Joseph Schacherer. Philosophical Proceedings of the Royal Society B. 2022. doi:10.1098/rstb.2020.0514 With the advent of…
Book chapter
RNA interference (RNAi) as a tool for high-resolution phenotypic screening of the pathogenic yeast Candida glabrata. Andreas Tsouris, Joseph Schacherer, Olena P. Ishchuk. Yeast Functional Genomics. 2022. doi:10.1007/978-1-0716-2257-5_18
New publication in Genomics
Towards accurate, contiguous and complete alignment-based polyploid phasing algorithms. Omar Abou Saada, Anne Friedrich, Joseph Schacherer. Genomics. 2022. doi:10.1016/j.ygeno.2022.110369 Phasing, and in particular polyploid phasing, have been challenging problems held back by the limited read…
New publication in Molecular Ecology
Brettanomyces bruxellensis: overview of the genetic and phenotypic diversity of an anthropized yeast. Jules Harrouard, Chris Eberlein, Patricia Ballestra, Marguerite Dols-Lafargue, Isabelle Masneuf-Pomarede, Cécile Miot-Sertier, Joseph Schacherer, Warren Albertin. Molecular Ecology. 2022. doi:…
New publication in Nature Ecology & Evolution
Domestication reprogrammed the budding yeast life cycle.