New publication of the MITO-team in NAR molecular Medicine
Mitochondrial CRISPR system : new paper in NAR Mol Med by the MITO-team
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A Trade-Off between Stress Resistance and Tolerance Underlies the Adaptive Response to Hydrogen Peroxide
Basile Jacquel, Bor Kavčič, Audrey Matifas, Thomas Julou, Gilles Charvin Cell Systems 16, 101320 (2025) - DOI: 10.1016/j.cels.2025.101320 In this work in collaboration with the Thomas Julou and Bruce Morgan lab, we investigated the mechanistic interplay between resistance and tolerance strategies in Saccharomyces cerevisiae subjected to…
New publication of the MITO team about endonuclease G
The MITO team participated in an international collaborative study with the National Heart, Lung and Blood Institute (NIH, Bethesda, MD, USA), now published in Proceedings of National Academy of Sciences of USA.
PFAS : En quête de recettes pour détruire les polluants éternels.
A la croisée des chemins entre chimie, biologie, physique et ingénierie, une équipe strasbourgeoise tente de repérer, dans des échantillons de sols contaminés, une bactérie qui se serait adaptée aux PFAS et pourrait avoir développé des enzymes capables de les dégrader (Le Monde, 11 décembre 2024).
News
New publication of the MITO-team in NAR molecular Medicine
Mitochondrial CRISPR system : new paper in NAR Mol Med by the MITO-team
New review article on LOH dynamics
The dynamics of loss of heterozygosity events in genomes. Abhishek Dutta, Joseph Schacherer. Genomic instability is a hallmark of tumorigenesis, yet…
New publication in PLos Genetics
Species-wide survey of the expressivity and complexity spectrum of traits in yeast. Andreas Tsouris, Téo Fournier, Anne Friedrich, Jing Hou, Maitreya…
Regards sur les ribozymes
Benoït Masquida, directeur de recherche CNRS au laboratoire de Génétique moléculaire, génomique et microbiologie (GMGM) nous explique les multiples…
Théo Aspert was awarded the 2022 SBS thesis prize
Théo Aspert was awarded a thesis prize by the Strasbourg Biology Society for his thesis "Deciphering the aging dynamics using microfluidics and…
An RNA to detect fluorine paving the way to the development of depollution enzymes
Find the latest publication (doi.org/10.1002/smll.202205232) of Claire HUSSER and Michael RYCKELYNCK (team “Digital Biology of RNA”) online on the…
New publication, team AIME: a bacterium feeding on metformin, a major antidiabetic drug and aquatic contaminant
A Methylotrophic Bacterium Growing with the Antidiabetic Drug, Metformin as Its Sole Carbon, Nitrogen and Energy Source. Chaignaud, Gruffaz, et al.…
Junior chairs in the field of research on mitochondria
The Laboratory of Excellence (LabEx) MitoCross announces the call for applications for two junior chairs in the field of research on mitochondria.
USIAS 2020 award for Alexandre Smirnov
The Institute for Advanced Studies at the University of Strasbourg (USIAS) is committed to supporting an original type of research and potentially…
PFAS : En quête de recettes pour détruire les polluants éternels.
A la croisée des chemins entre chimie, biologie, physique et ingénierie, une équipe strasbourgeoise tente de repérer, dans des échantillons de sols…
Strasbourg : à la recherche de la « super-bactérie » (DNA ; 17/01/24)
À l’université de Strasbourg, des chercheurs traquent les micro-organismes qui pourraient un jour gommer certains des micropolluants qui s’accumulent…
Montrer les invisibles du sol : dialogue entre étudiants en design et microbiologistes de l’équipe AIME du GMGM
Montrer les invisibles du sol : dialogue entre étudiants en design et microbiologistes de l’équipe AIME du GMGM 14 octobre 2023 : ‘École Vivrière’…
New publication of Emilie MULLER (team AIME) in Nature Ecology & Evolution
Microbiomes are essential for safeguarding health in humans and the environment, and are central to sustainability. A key microbiome-based technology…
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Spotlight
Quand l’évolution s’invite au labo
Alexandre Smirnov a parlé de l’évolution expérimentale dans le cadre des "Rencontres" du « Jardin des Sciences de l’Université de Strasbourg » (Palais…
Spotlight
Bacteria, mitochondria, ribosomes & evolution at the Fête de la Science 2023
Friday, October 13, 2023 was the school day in the Village des Sciences, at the Palais Universitaire. The MITO team was there to familiarise the…
Front publications
A Trade-Off between Stress Resistance and Tolerance Underlies the Adaptive Response to Hydrogen Peroxide
Basile Jacquel, Bor Kavčič, Audrey Matifas, Thomas Julou, Gilles Charvin Cell Systems 16, 101320 (2025) - DOI: 10.1016/j.cels.2025.101320 In…
New publication of the MITO team about endonuclease G
The MITO team participated in an international collaborative study with the National Heart, Lung and Blood Institute (NIH, Bethesda, MD, USA), now…
New publication from the Becker & Tarassov-Smirnov teams: AARS Online: A collaborative database on the structure, function, and evolution of the aminoacyl-tRNA synthetases
AARS Online is an interactive Wikipedia-like tool curated by an international consortium of aminoacyl-tRNA synthetase (aaRS) experts. Accessible at…
New publication in Nature Cell Biology by the MITO team in collaboration with the University of Liège
Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma. doi.org/10.1038/s41556-024-01439-2 Transfer RNA dynamics contribute to…
New publication in collaboration
Natural proteome diversity links aneuploidy tolerance to protein turnover. Julia Muenzner, Pauline Trébulle, Federica Agostini, Henrik Zauber,…
New publication in Nature Genetics
Pan-transcriptome reveals a large accessory genome contribution to gene expression variation in yeast. Élodie Caudal, Victor Loegler, Fabien Dutreux,…
New publication in PNAS
Species-wide quantitative transcriptomes and proteomes reveal distinct genetic control of gene expression variation in yeast. Elie M Teyssonnière,…
New publication in collaboration
Absence of chromosome axis protein recruitment prevents meiotic recombination chromosome-wide in the budding yeast Lachancea kluyveri. Sylvain…
New publication of the team
Diallel panel reveals a significant impact of low-frequency genetic variants on gene expression variation in yeast. Andreas Tsouris, Gauthier Brach,…
New publication in NAR
Translation variation across genetic backgrounds reveals a post-transcriptional buffering signature in yeast. Elie M Teyssonniere, Yuichi Shichino,…
New publication in Cell Genomics
Non-additive genetic components contribute significantly to population-wide gene expression variation. Andreas Tsouris, Gauthier Brach, Joseph…
New publication by MITO-team
Targeting of CRISPR-Cas12a crRNAs into human mitochondria
New publication in Nature Genetics
Telomere-to-telomere assemblies of 142 strains characterize the genome structural landscape in Saccharomyces cerevisiae. Samuel O’Donnell, Jia-Xing…
New publication in collabration
Copy number variation alters local and global mutational tolerance. Grace Avecilla, Pieter Spealman, Julia Matthews, Elodie Caudal, Joseph Schacherer,…
New publication in G3
Impact of the acquired subgenome on the transcriptional landscape in Brettanomyces bruxellensis allopolyploids. Arthur Jallet, Anne Friedrich, Joseph…
New publication in Genome Biology and Evolution
Contrasting genomic evolution between domesticated and wild Kluyveromyces lactis yeast populations. Anne Friedrich, Jean-Sébastien Gounot, Andreas…
À propos du GMGM
Génétique Moléculaire, Génomique, Microbiologie
Le laboratoire GMGM étudie les mécanismes fondamentaux du fonctionnement et des dysfonctionnements des génomes de cellules procaryotiques et eucaryotiques ainsi que de divers processus intracellulaires.