A position is open for a post-doctoral / engineer in Microbial Environmental Bio-informatics for a 12-month contract, funded by the French and Indian collaboration program IFCPAR. The Project: Phyllosphere methylotroph driven bioconversion of atmospheric greenhouse gas and volatiles to plant…
Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma. doi.org/10.1038/s41556-024-01439-2 Transfer RNA dynamics contribute to cancer development through regulation of codon-specific messenger RNA translation. Specific aminoacyl-tRNA synthetases can either promote or suppress…
Natural proteome diversity links aneuploidy tolerance to protein turnover. Julia Muenzner, Pauline Trébulle, Federica Agostini, Henrik Zauber, Christoph B. Messner, Martin Steger, Christiane Kilian, Kate Lau, Natalie Barthel, Andrea Lehmann, Kathrin Textoris-Taube, Elodie Caudal, Anna-Sophia Egger,…
Pan-transcriptome reveals a large accessory genome contribution to gene expression variation in yeast. Élodie Caudal, Victor Loegler, Fabien Dutreux, Nikolaos Vakirlis, Élie Teyssonnière, Claudia Caradec, Anne Friedrich, Jing Hou, Joseph Schacherer. Nature Genetics. 2024. doi:…
Species-wide quantitative transcriptomes and proteomes reveal distinct genetic control of gene expression variation in yeast. Elie M Teyssonnière, Pauline Trébulle, Julia Muenzner, Joseph Schacherer. PNAS. 2024. doi:10.1073/pnas.2319211121 Gene expression varies between individuals and corresponds…
A position is open for a post-doctoral / engineer in Microbial Environmental Bio-informatics for a 12-month contract,…
Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma. doi.org/10.1038/s41556-024-01439-2 Transfer…
Natural proteome diversity links aneuploidy tolerance to protein turnover. Julia Muenzner, Pauline Trébulle, Federica…
Pan-transcriptome reveals a large accessory genome contribution to gene expression variation in yeast. Élodie Caudal,…
Species-wide quantitative transcriptomes and proteomes reveal distinct genetic control of gene expression variation in…
Absence of chromosome axis protein recruitment prevents meiotic recombination chromosome-wide in the budding yeast Lacha…
Diallel panel reveals a significant impact of low-frequency genetic variants on gene expression variation in yeast.…
Translation variation across genetic backgrounds reveals a post-transcriptional buffering signature in yeast. Elie M…
Species-wide survey of the expressivity and complexity spectrum of traits in yeast. Andreas Tsouris, Téo Fournier, Anne…
À l’université de Strasbourg, des chercheurs traquent les micro-organismes qui pourraient un jour gommer certains des…
Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma. doi.org/10.1038/s41556-024-01439-2 Transfer RNA dynamics contribute to cancer development through regulation of codon-specific messenger RNA translation. Specific aminoacyl-tRNA synthetases can either promote or suppress…
Natural proteome diversity links aneuploidy tolerance to protein turnover. Julia Muenzner, Pauline Trébulle, Federica Agostini, Henrik Zauber, Christoph B. Messner, Martin Steger, Christiane Kilian, Kate Lau, Natalie Barthel, Andrea Lehmann, Kathrin Textoris-Taube, Elodie Caudal, Anna-Sophia Egger,…
Pan-transcriptome reveals a large accessory genome contribution to gene expression variation in yeast. Élodie Caudal, Victor Loegler, Fabien Dutreux, Nikolaos Vakirlis, Élie Teyssonnière, Claudia Caradec, Anne Friedrich, Jing Hou, Joseph Schacherer. Nature Genetics. 2024. doi:…
Species-wide quantitative transcriptomes and proteomes reveal distinct genetic control of gene expression variation in yeast. Elie M Teyssonnière, Pauline Trébulle, Julia Muenzner, Joseph Schacherer. PNAS. 2024. doi:10.1073/pnas.2319211121 Gene expression varies between individuals and corresponds…
Absence of chromosome axis protein recruitment prevents meiotic recombination chromosome-wide in the budding yeast Lachancea kluyveri. Sylvain Legrand, Asma Saifudeen, Hélène Bordelet, Julien Vernerey, Arnaud Guille, Amaury Bignaud, Agnès Thierry, Laurent Acquaviva, Maxime Gaudin, Aurore Sanchez,…
Diallel panel reveals a significant impact of low-frequency genetic variants on gene expression variation in yeast. Andreas Tsouris, Gauthier Brach, Anne Friedrich, Jing Hou, Joseph Schacherer. Mol Syst Biol. 2024. doi:10.1038/s44320-024-00021-0 Unraveling the genetic sources of gene expression…
Translation variation across genetic backgrounds reveals a post-transcriptional buffering signature in yeast. Elie M Teyssonniere, Yuichi Shichino, Mari Mito, Anne Friedrich, Shintaro Iwasaki, Joseph Schacherer. Nucleic Acids Research. 2024. doi:10.1093/nar/gkae030 Gene expression is known to…
Non-additive genetic components contribute significantly to population-wide gene expression variation. Andreas Tsouris, Gauthier Brach, Joseph Schacherer, Jing Hou. Gene expression variation, an essential step between genotype and phenotype, is collectively controlled by local (cis) and distant (tr…
Our comprehensive review on the fascinating ribosome assembly GTPase Era/ERAL1 is out!
Anyone who wants to have a clear & reliable idea about RNA localisation inside/outside membrane-bounded organelles, extracellular vesicles, or viral particles can now use this detailed protocol. It includes all reagents & equipment necessary to perform CoLoC-seq experiments, a step-by-step protocol,…
Targeting of CRISPR-Cas12a crRNAs into human mitochondria
Telomere-to-telomere assemblies of 142 strains characterize the genome structural landscape in Saccharomyces cerevisiae. Samuel O’Donnell, Jia-Xing Yue, Omar Abou Saada, Nicolas Agier, Claudia Caradec, Thomas Cokelaer, Matteo De Chiara, Stéphane Delmas, Fabien Dutreux, Téo Fournier, Anne Friedrich,…
Copy number variation alters local and global mutational tolerance. Grace Avecilla, Pieter Spealman, Julia Matthews, Elodie Caudal, Joseph Schacherer, David Gresham. Copy number variants (CNVs), duplications and deletions of genomic sequences, contribute to evolutionary adaptation but can also…
Impact of the acquired subgenome on the transcriptional landscape in Brettanomyces bruxellensis allopolyploids. Arthur Jallet, Anne Friedrich, Joseph Schacherer. G3 Genes|Genomes|Genetics. 2023. doi:10.1093/g3journal/jkad115 Gene expression variation can provide an overview of the changes in…
Our review paper on the evolutionary significance of RNA-binding proteins of the FinO/ProQ family has been published in Bioscience Reports.
Contrasting genomic evolution between domesticated and wild Kluyveromyces lactis yeast populations. Anne Friedrich, Jean-Sébastien Gounot, Andreas Tsouris, Claudine Bleykasten, Kelle Freel, Claudia Caradec, Joseph Schacherer. Genome Biology and Evolution. 2023. doi:10.1093/gbe/evad004 The process…
Le laboratoire GMGM étudie les mécanismes fondamentaux du fonctionnement et des dysfonctionnements des génomes de cellules procaryotiques et eucaryotiques ainsi que de divers processus intracellulaires.
