Montrer les invisibles du sol : dialogue entre étudiants en design et microbiologistes de l’équipe AIME du GMGM 14 octobre 2023 : ‘École Vivrière’ au CSC de la Roberstau à Strasbourg (https://www.lyceelecorbusier.eu/dsaa/?p=3730) Les étudiant.e.s d’arts appliqués du Lycée le Corbusier à…
Microbiomes are essential for safeguarding health in humans and the environment, and are central to sustainability. A key microbiome-based technology is biological wastewater treatment, the most widely used biotechnological process on Earth. The process itself is subject to constant changes and does…
GMGM a organisé et présenté la fête de la Science à Lingolsheim du 6 au 8 octobre 2023.
Friday, October 13, 2023 was the school day in the Village des Sciences, at the Palais Universitaire. The MITO team was there to familiarise the "youngest generation of scientists" with bases of cellular and molecular biology.
Targeting of CRISPR-Cas12a crRNAs into human mitochondria
Montrer les invisibles du sol : dialogue entre étudiants en design et microbiologistes de l’équipe AIME du GMGM 14…
Microbiomes are essential for safeguarding health in humans and the environment, and are central to sustainability. A…
GMGM a organisé et présenté la fête de la Science à Lingolsheim du 6 au 8 octobre 2023.
Friday, October 13, 2023 was the school day in the Village des Sciences, at the Palais Universitaire. The MITO team was…
Targeting of CRISPR-Cas12a crRNAs into human mitochondria
Telomere-to-telomere assemblies of 142 strains characterize the genome structural landscape in Saccharomyces cerevisiae.…
Copy number variation alters local and global mutational tolerance. Grace Avecilla, Pieter Spealman, Julia Matthews,…
Benoït Masquida, directeur de recherche CNRS au laboratoire de Génétique moléculaire, génomique et microbiologie (GMGM)…
Impact of the acquired subgenome on the transcriptional landscape in Brettanomyces bruxellensis allopolyploids. Arthur…
La Société de Biologie de Strasbourg (SBS) a décerné un prix à Théo Aspert pour sa thèse "Élucidation de la dynamique de…
Our comprehensive review on the fascinating ribosome assembly GTPase Era/ERAL1 is out!
Anyone who wants to have a clear & reliable idea about RNA localisation inside/outside membrane-bounded organelles, extracellular vesicles, or viral particles can now use this detailed protocol. It includes all reagents & equipment necessary to perform CoLoC-seq experiments, a step-by-step protocol,…
Targeting of CRISPR-Cas12a crRNAs into human mitochondria
Impact of the acquired subgenome on the transcriptional landscape in Brettanomyces bruxellensis allopolyploids. Arthur Jallet, Anne Friedrich, Joseph Schacherer. G3 Genes|Genomes|Genetics. 2023. doi:10.1093/g3journal/jkad115 Gene expression variation can provide an overview of the changes in…
Our review paper on the evolutionary significance of RNA-binding proteins of the FinO/ProQ family has been published in Bioscience Reports.
Contrasting genomic evolution between domesticated and wild Kluyveromyces lactis yeast populations. Anne Friedrich, Jean-Sébastien Gounot, Andreas Tsouris, Claudine Bleykasten, Kelle Freel, Claudia Caradec, Joseph Schacherer. Genome Biology and Evolution. 2023. doi:10.1093/gbe/evad004 The process…
Lessons from the meiotic recombination landscape of the ZMM deficient budding yeast Lachancea waltii. Fabien Dutreux, Abhishek Dutta, Emilien Peltier, Sabrina Bibi-Triki, Anne Friedrich, Bertrand Llorente, Joseph Schacherer. PLoS Genet. 2023. doi:10.1371/journal.pgen.1010592 Meiotic recombination…
We are proud to present a great collection of papers published in the Special issue "Research progress in RNA-binding proteins" of International Journal of Molecular Sciences - editorial by Alexandre Smirnov.
A new genome-wide method that marries classical enzymatic kinetics, deep sequencing, and mathematical modelling - CoLoC-seq - has been created in the MITO team and successfully applied to human mitochondria to tell resident RNAs from contaminants.
Editorial for a special issue of Frontiers Physiology
Theoretical and mathematical biology paper about hub-centred RNA-protein networks
Loss of heterozygosity spectrum depends on ploidy level in natural yeast populations. Abhishek Dutta, Fabien Dutreux, Joseph Schacherer. Molecular Biology and Evolution. 2022. doi:10.1093/molbev/msac214 The appearance of genomic variations such as loss of heterozygosity (LOH) has a significant…
Loss-of-function mutation survey revealed that genes with background-dependent fitness are rare and functionally related in yeast. Elodie Caudal, Anne Friedrich, Arthur Jallet, Marion Garin, Jing Hou, Joseph Schacherer. Proc Natl Acad Sci U S A. 2022. doi:10.1073/pnas.2204206119 In natural…
Extensive simulations assess the performance of genome-wide association mapping in various Saccharomyces cerevisiae subpopulations. Jackson Peter, Anne Friedrich, Gianni Liti, Joseph Schacherer. Philosophical Proceedings of the Royal Society B. 2022. doi:10.1098/rstb.2020.0514 With the advent of…
RNA interference (RNAi) as a tool for high-resolution phenotypic screening of the pathogenic yeast Candida glabrata. Andreas Tsouris, Joseph Schacherer, Olena P. Ishchuk. Yeast Functional Genomics. 2022. doi:10.1007/978-1-0716-2257-5_18
Towards accurate, contiguous and complete alignment-based polyploid phasing algorithms. Omar Abou Saada, Anne Friedrich, Joseph Schacherer. Genomics. 2022. doi:10.1016/j.ygeno.2022.110369 Phasing, and in particular polyploid phasing, have been challenging problems held back by the limited read…
Le laboratoire GMGM étudie les mécanismes fondamentaux du fonctionnement et des dysfonctionnements des génomes de cellules procaryotiques et eucaryotiques ainsi que de divers processus intracellulaires.
