Loss of heterozygosity spectrum depends on ploidy level in natural yeast populations. Abhishek Dutta, Fabien Dutreux, Joseph Schacherer. Molecular Biology and Evolution. 2022. doi:10.1093/molbev/msac214 The appearance of genomic variations such as loss of heterozygosity (LOH) has a significant…
Loss-of-function mutation survey revealed that genes with background-dependent fitness are rare and functionally related in yeast. Elodie Caudal, Anne Friedrich, Arthur Jallet, Marion Garin, Jing Hou, Joseph Schacherer. Proc Natl Acad Sci U S A. 2022. doi:10.1073/pnas.2204206119 In natural…
Extensive simulations assess the performance of genome-wide association mapping in various Saccharomyces cerevisiae subpopulations. Jackson Peter, Anne Friedrich, Gianni Liti, Joseph Schacherer. Philosophical Proceedings of the Royal Society B. 2022. doi:10.1098/rstb.2020.0514 With the advent of…
RNA interference (RNAi) as a tool for high-resolution phenotypic screening of the pathogenic yeast Candida glabrata. Andreas Tsouris, Joseph Schacherer, Olena P. Ishchuk. Yeast Functional Genomics. 2022. doi:10.1007/978-1-0716-2257-5_18
Towards accurate, contiguous and complete alignment-based polyploid phasing algorithms. Omar Abou Saada, Anne Friedrich, Joseph Schacherer. Genomics. 2022. doi:10.1016/j.ygeno.2022.110369 Phasing, and in particular polyploid phasing, have been challenging problems held back by the limited read…
Brettanomyces bruxellensis: overview of the genetic and phenotypic diversity of an anthropized yeast. Jules Harrouard, Chris Eberlein, Patricia Ballestra, Marguerite Dols-Lafargue, Isabelle Masneuf-Pomarede, Cécile Miot-Sertier, Joseph Schacherer, Warren Albertin. Molecular Ecology. 2022. doi:…
Domestication reprogrammed the budding yeast life cycle.
Phased polyploid genomes provide deeper insight into the multiple origins of domesticated Saccharomyces cerevisiae beer yeasts.
Efficient target cleavage by Type V Cas12a effectors programmed with split CRISPR RNA Nucleic Acids Res. 2021 Dec 24. pii: gkab1227. doi: 10.1093/nar/gkab1227. Online ahead of print. Regina Shebanova 1, Natalia Nikitchina 1 2, Nikita Shebanov 1, Vladimir Mekler 3, Konstantin Kuznedelov 3, Egor…
Different trajectories of polyploidization shape the genomic landscape of the Brettanomyces bruxellensis yeast species.
Loss of heterozygosity results in rapid but variable genome homogenization across yeast genetic backgrounds.
Species-wide transposable element repertoires retrace the evolutionary history of the Saccharomyces cerevisiae host.
Sex without crossing over in the yeast Saccharomycodes ludwigii.
The FASEB Journal Early View RESEARCH ARTICLE Open Access Staphylococcus aureus Panton-Valentine Leukocidin triggers an alternative NETosis process targeting mitochondria Viola Mazzoleni Gaëlle Zimmermann-Meisse Anna Smirnova Ivan Tarassov Gilles Prévost First…
Discordant evolution of mitochondrial and nuclear yeast genomes at population level.
YBEY is an essential biogenesis factor for mitochondrial ribosomes Nucleic Acids Res. 2020 Mar 17. pii: gkaa148. doi: 10.1093/nar/gkaa148. [Epub ahead of print] Summer S1, Smirnova A2, Gabriele A2, Toth U1, Fasemore AM3, Förstner KU3,4,5, Kuhn L6, Chicher J6, Hammann P6, Mitulovi? G7, Entelis N2, …
IUBMB Life. 2018 Sep 5. doi: 10.1002/iub.1919. [Epub ahead of print] Can Mitochondrial DNA be CRISPRized: Pro and Contra. Loutre R1, Heckel AM1, Smirnova A1, Entelis N1, Tarassov I1. Author information Abstract Mitochondria represent a chimera of macromolecules encoded either in the…
R. Loutre, AM Heckel, D Jeandard, I Tarassov, N Entelis (2018) "Anti-replicative recombinant 5S rRNA molecules can modulate the mtDNA heteroplasmy in a glucose-dependent manner" PLOS ONE https://doi.org/10.1371/journal.pone.0199258 Abstract Mutations in mitochondrial DNA are an important source of…
Nouvel article publié dans la revue Frontiers in Microbiology dans le cadre du Research topic Using Genomics, Metagenomics and Other "Omics" to Assess Valuable Microbial Ecosystem Services and Novel Biotechnological Applications A Genomic Outlook on Bioremediation: The Case of Arsenic Removal…
