New publication of the MITO team in Computational and Structural Biotechnology Journal
Theoretical and mathematical biology paper about hub-centred RNA-protein networks
New publication in Molecular Biology and Evolution
Loss of heterozygosity spectrum depends on ploidy level in natural yeast populations. Abhishek Dutta, Fabien Dutreux, Joseph Schacherer. Molecular Biology and Evolution. 2022. doi:10.1093/molbev/msac214 The appearance of genomic variations such as loss of heterozygosity (LOH) has a significant…
New publication in PNAS
Loss-of-function mutation survey revealed that genes with background-dependent fitness are rare and functionally related in yeast. Elodie Caudal, Anne Friedrich, Arthur Jallet, Marion Garin, Jing Hou, Joseph Schacherer. Proc Natl Acad Sci U S A. 2022. doi:10.1073/pnas.2204206119 In natural…
New publication
Extensive simulations assess the performance of genome-wide association mapping in various Saccharomyces cerevisiae subpopulations. Jackson Peter, Anne Friedrich, Gianni Liti, Joseph Schacherer. Philosophical Proceedings of the Royal Society B. 2022. doi:10.1098/rstb.2020.0514 With the advent of…
Book chapter
RNA interference (RNAi) as a tool for high-resolution phenotypic screening of the pathogenic yeast Candida glabrata. Andreas Tsouris, Joseph Schacherer, Olena P. Ishchuk. Yeast Functional Genomics. 2022. doi:10.1007/978-1-0716-2257-5_18
New publication in Genomics
Towards accurate, contiguous and complete alignment-based polyploid phasing algorithms. Omar Abou Saada, Anne Friedrich, Joseph Schacherer. Genomics. 2022. doi:10.1016/j.ygeno.2022.110369 Phasing, and in particular polyploid phasing, have been challenging problems held back by the limited read…
New publication in Molecular Ecology
Brettanomyces bruxellensis: overview of the genetic and phenotypic diversity of an anthropized yeast. Jules Harrouard, Chris Eberlein, Patricia Ballestra, Marguerite Dols-Lafargue, Isabelle Masneuf-Pomarede, Cécile Miot-Sertier, Joseph Schacherer, Warren Albertin. Molecular Ecology. 2022. doi:…
New publication in Nature Ecology & Evolution
Domestication reprogrammed the budding yeast life cycle.
New publication in Current Biology
Phased polyploid genomes provide deeper insight into the multiple origins of domesticated Saccharomyces cerevisiae beer yeasts.
New publication of the MITO team in Nucleic Acids Research
Efficient target cleavage by Type V Cas12a effectors programmed with split CRISPR RNA Nucleic Acids Res. 2021 Dec 24. pii: gkab1227. doi: 10.1093/nar/gkab1227. Online ahead of print. Regina Shebanova 1, Natalia Nikitchina 1 2, Nikita Shebanov 1, Vladimir Mekler 3, Konstantin Kuznedelov 3, Egor…
New publication in Genome Research
Different trajectories of polyploidization shape the genomic landscape of the Brettanomyces bruxellensis yeast species.
New publication in eLife
Loss of heterozygosity results in rapid but variable genome homogenization across yeast genetic backgrounds.
New publication in Molecular Biology and Evolution
Species-wide transposable element repertoires retrace the evolutionary history of the Saccharomyces cerevisiae host.
A FASEB J. paper by the MITO team
The FASEB Journal Early View RESEARCH ARTICLE Open Access Staphylococcus aureus Panton-Valentine Leukocidin triggers an alternative NETosis process targeting mitochondria Viola Mazzoleni Gaëlle Zimmermann-Meisse Anna Smirnova Ivan Tarassov Gilles Prévost First…
New publication in BMC Biology
Discordant evolution of mitochondrial and nuclear yeast genomes at population level.
New publication of the MITO team in Nucleic Acids Research
YBEY is an essential biogenesis factor for mitochondrial ribosomes Nucleic Acids Res. 2020 Mar 17. pii: gkaa148. doi: 10.1093/nar/gkaa148. [Epub ahead of print] Summer S1, Smirnova A2, Gabriele A2, Toth U1, Fasemore AM3, Förstner KU3,4,5, Kuhn L6, Chicher J6, Hammann P6, Mitulovi? G7, Entelis N2, …
Equipe EM2
Nouvel article publié dans la revue Frontiers in Microbiology dans le cadre du Research topic Using Genomics, Metagenomics and Other "Omics" to Assess Valuable Microbial Ecosystem Services and Novel Biotechnological Applications A Genomic Outlook on Bioremediation: The Case of Arsenic Removal…
Papier dans Methods Equipe Becker et Friant
Nonconventional localizations of cytosolic aminoacyl-tRNA synthetases in yeast and human cells Sylvain Debard, Gaétan Bader, Johan-Owen De Craene, Ludovic Enkler, Séverine Bär, Daphné Laporte, Evelyne Myslinski, Bruno Senger, Sylvie Friant, Hubert Dominique Becker.