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Membrane traffic and lipid signalization

Head of the group : Dr Sylvie Friant

We use the yeast Saccharomyces cerevisiae, primary cells from patients and mice (knock-out and knock-in) cells and tissues as models to study human genes involved in diseases et coding for proteins of the membrane trafficking.

Fluorescence microscopy

Wild type yeast cells (on the left) and ent3 ent5 mutant cells (on the right) observed with a fluorecence microscope after endosome staining with FM4-64(red) and vacuolar staining with CMAC (Blue)