Lab news
2018
April 2018
The 1011 S. cerevisiae genomes in Nature :
Genome evolution across 1,011 Saccharomyces cerevisiae isolates
in collaboration with G. Liti and the Génoscope.
An here is the associated press review:
Behind the paper, Natureecoevocommunity
New & Noteworthy, SGD
L'actualité de la recherche, Université de Strasbourg
The Atlantic
Danmarks Radio
Focus.it
Phys.org
GeneticLiteracyProject
Congrats2 !!!
Elodie won the prize for her presentation at the Séminaire de Microbiologie de Strasbourg (SMS18).
Jackson was awarded the prize Prix de thèse 2018 of the Université de Strasbourg.
Funding: the team obtains an IdEx 2018 Postdoctorant fellowship "Population-scale exploration of the phenotypic expressivity".
A new article in collaboration :
Brettanomyces bruxellensis population survey reveals a diploid-triploid complex structured according to substrate of isolation and geographical distribution.
January 2018
Welcome to Adrien Perrin for his Master training.
2017
December 2017
Joseph Schacherer was awarded an ERC Consolidator grant for his research proposal "Inheritance, expressivity and epistasis hidden behind the phenotypic landscape of natural populations".
September 2017
The team welcomes three new members:
Elodie Caudal and Omar Abou-Saada, PhD students and Sabrina Bibi-Triki, post-doc.
Jackson Peter will defend his PhD thesis:
«Dissection de la relation génotype-phénotype par des études d'association chez Saccharomyces cerevisiae»
septembre 25, 10 am, amphithéâtre du Collège Doctoral Européen.
New publication of the team:
Genetic backgrounds and hidden trait complexity in natural populations.
New publication in collaboration:
Identification of a novel interspecific hybrid yeast from a metagenomic spontaneously inoculated beer sample using Hi-C.
August 2017
Two new publications of the team:
Variation of the meiotic recombination landscape and properties over a broad evolutionary distance in yeasts.
Two publications in collaboration:
Yeast-bacteria competition induced new metabolic traits through large-scale genomic rearrangements in Lachancea kluyveri.
Phenotypic diagnosis of lineage and differentiation during sake yeast breeding.
March 2017
Congrats to Jing Hou for her price 'prix de thèse Transgène de la Société de Biologie de Strasbourg'.
February 2017
The project 'Elucidating how traits are heritable through functional and population genomics across a whole subphylum' is awarded a USIAS Fellow (Institut d’Études Avancées de l'Université de Strasbourg).
New publication in collaboration with Eric Alani: Mismatch Repair Incompatibilities in Diverse Yeast Populations.
about the paper: http://www.yeastgenome.org/the-dark-yeast-rises
January 2017
Téo Fournier mid-thesis: 'Towards a species-wide view of the genetic architecture of traits'.
Friday 20 january, 14 PM, Salle d'Alsace (Botanique).
New publication in collaboration with the Génoscope: de novo assembly and population genomic survey of natural yeast isolates with the Oxford Nanopore MinION sequencer.
2016
December 2016
Congrats!
Joseph Schacherer is laureate of the prize Guy Ourisson-Cercle Gutenberg.
The NIH R01 Grant is renewed, for collaborative research with Maitreya Dunham (Washington University, Seattle, USA) and David Hess (University of Santa Clara, Santa Clara, USA).
October 2016
New publication of the team in Mol Biol Evol : Fitness trade-offs lead to suppressor tolerance in yeast.
Performance of the team at EKIDEN de Strasbourg 2016:
rank 123 (Diploteam); 3h-56min-25sec:
Elodie 5 km ; (00:34:25)
Téo 10 km ; (00:44:35)
Marion 5 km ; (00:36:18)
Fifou/Joseph 10 km ; (00:47:50)
Claudine 5 km ; (00:31:24)
Anne 7.5 km ; (00:41:51)
September 2016
The team welcomes Roméo and Elodie for their master training courses.
Awarding of the Espoirs de l'Université de Strasbourg for Anne Friedrich and celebration of the nomination of Joseph Schacherer at the Institut Universitaire de France: videos are here.
July 2016
The lab has been awarded an ANR Program Grant (PhenoVar project) for collaborative research with Gilles Fischer (UPMC, Paris) and Gianni Liti (IRCAN, Nice).
New publication in Cell Reports:
The hidden complexity of mendelian traits across natural yeast populations.
and the corresponding article from the CNRS: Quand le génétiquement simple devient complexe !
New publication of the team: Dissection of quantitative traits by bulk segregant mapping in a protoploid yeast species.
June 2016
Congrats to Anastasie Sigwalt for her PhD defense (3 june).
New article in collaboration with Gilles Fischer:
Reconstruction of ancestral chromosome architecture and gene repertoire reveals principles of genome evolution in a model yeast genus.
Nikolaos Vakirlis, Véronique Sarilar, Guénola Drillon, Aubin Fleiss, Nicolas Agier, Jean-Philippe Meyniel, Lou Blanpain, Alessandra Carbone, Hugo Devillers, Kenny Dubois, Alexandre Gillet-Markowska, Stéphane Graziani, Nguyen Huu-Vang, Marion Poirel, Cyrielle Reisser, Jonathan Schott, Joseph Schacherer, Ingrid Lafontaine, Bertrand Llorente, Cécile Neuvéglise and Gilles Fischer.
Genome Research. 2016, doi: 10.1101/gr.204420.116.
Two new publications:
Beyond the simplicity of Mendelian inheritance.
Joseph Schacherer.
Comptes Rendus Biologies. 2016, doi:10.1016/j.crvi.2016.04.006.
Species-wide survey reveals the various flavors of intraspecific reproductive isolation in yeast.
Jing Hou, Téo Fournier, Joseph Schacherer.
FEMS Yeast Res. 2016, doi: 10.1093/femsyr/fow048.
May 2016
Congrats !
Joseph Schacherer is nominated at the Institut Universitaire de France.
Anne Friedrich is among the scientific prize laureates Espoirs de l’Université de Strasbourg.
March 2016
Jing Hou defended her PhD thesis entitled: 'Species-wide survey reveals the complex landscape of the genetic origin of reproductive isolation within natural yeast populations.'
New publication of the team:
Differences in environmental stress response between yeasts is consistent with species-specific lifestyles.
February 2016
Welcome to Manuel Majrouh (M1 Bioinfo) for his training.
new publications of the team:
Large-Scale Survey of Intraspecific Fitness and Cell Morphology Variation in a Protoploid Yeast Species.
Paul P. Jung, Anastasie Sigwalt, Shinsuke Ohnuki, Jacky de Montigny, Yoshikazu Ohya, Joseph Schacherer.
G3. 2016, doi: 10.1534/g3.115.026682.
The hidden complexity of Mendelian traits across yeast natural populations.
Jing Hou, Anastasie Sigwalt, David Pflieger, Jackson Peter, Jacky de Montigny, Maitreya Dunham, Joseph Schacherer.
Biorxivpreprint. 2016, doi: dx.doi.org/10.1101/039693.
January 2016
Jean-Sébastien Gounot mid-thesis presentation: "Exploration de la diversité génétique intraspécifique au sein des levures hémiascomycètes", friday 29 january, 14 PM, salle d'Alsace.
New publication of the team in Genome Biol Evol:
Whole-genome sequencing and intraspecific analysis of the yeast species Lachancea quebecensis.
Welcome to Arnaud Fertet (Master 2 student) and Carolyn Schneider (L3-Erasmus).
2015
November 2015
New review of the team on population genomics:
Population genomics of yeasts: Towards a comprehensive view across a broad evolutionary scale.
October 2015
The results of the team at the Marathon de Strasbourg 2015:
*Marathon: Joseph Schacherer
03:17:05 85e
*Duo: Kelle Freel and Christian Brion
03:08:06 19e
*Ekiden: Haploteam (Anne Fridedrich, Jacky de Montigny, Jackson Peter, Téo Fournier, Jean-Sébastien Gounot, Arnaud Fertet)
03:45:24 93e
New publication of the team:
On the Mapping of Epistatic Genetic Interactions in Natural Isolates: Combining Classical Genetics and Genomics.
August 2015
A new yeast species described by the group: Lachancea quebecensis sp. nov., a yeast species consistently isolated from tree bark in the Canadian province of Québec.
July 2015
New publication of the team:
Negative epistasis: a route to intraspecific reproductive isolation in yeast?
Congratulations to Téo Fournier on his PhD University Fellowship!
Illustration of Anne’s talk by Alex Cagan at the SMBE 2015 Meeting:
June 2015
New website for our large-scale sequencing projet: « The 1002 Yeast Genomes Project » 1002genomes.u-strasbg.fr
New insights on our Nature Communications paper in SGD (Saccharomyces Genome Database):
'The Failed Hook Up: A Sitcom Starring S. cerevisiae', Université de Strasbourg: 'Les origines génétiques de la spéciation chez la levure' and CNRS: 'Les génomes incompatibles ne font pas bon ménage !'
Congratulations to Jing Hou on her La Ligue Contre le Cancer Fellowship!
May 2015
New publication of the team in Nature Communications :
Comprehensive survey of condition-specific reproductive isolation reveals genetic incompatibility in yeast.
Our review on yeast mitochondrial genome evolution just came out:
Mitochondrial genome evolution in yeasts: an all-encompassing view.
April 2015
New publication of the team in Nucleic Acids Research:
Evolution of intraspecific transcriptomic landscapes in yeasts.
New publication in collaboration:
Draft genome sequence of Lachancea lanzarotensis CBS 12615T, an ascomycetous yeast isolated from grapes.
January 2015
Welcome to Téo, Morand and Sirine (undergraduate students).
2014
December 2014
New publication in collaboration, in Genome Biology and Evolution:
Evolutionary dynamics of hAT DNA transposon families in Saccharomycetaceae.
October 2014
Marathon de Strasbourg-2014
The team participated to the latest marathon of Strasbourg on October 26th. Pretty good results, indeed:
*Marathon (Christian Brion)
03:08:58 49e
*Duo (Kelle Freel et Joseph Schacherer)
03:19:53 4e duo mixte
*Ekiden (Anne Fridedrich, de Montigny Jacky, Jing Hou, David Plfiger, Cyrielle Reisser, Morand Silber)
03:53:50 88e
*Ekiden (Cecilia Garmendia, Lize Braat, Anastasie Sigwalt, Téo Fournier, Jean-Seb Gounot, Jackson Peter)
03:54:05 92e
New publication of the team in Molecular Biology and Evolution:
Population genomics reveals chromosome-scale heterogeneous evolution in a protoploid yeast
September 2014
New publication of the team in Genome Biology and Evolution:
Population genomic analysis reveals highly conserved mitochondrial genomes in the yeast species Lachancea thermotolerans.
August 2014
New publication of the team:
Genome sequence of the yeast Cyberlindnera fabianii (Hansenula fabianii).
Genome Announc. 2014 Aug 7;2(4).
Jing Hou is awarded the prize "article du mois - Août 2014" SFBBM
July 2014
Congratulations to Jean-sébastien Gounot on his PhD University Fellowship!
June 2014
Congrats!
Joseph Schacherer is among the scientific prize laureates « les Espoirs de l’Université de Strasbourg »
Read also in ACTU_unistra
May 2014
New publication of the team in Current Biology:
Chromosomal rearrangements as a major mechanism in the onset of reproductive isolation in Saccharomyces cerevisiae.
Curr Biol. 2014 May 19;24(10):1153-9.
Our article acknoledged:
- our article is referred by Clifford Zeyl: Evolution: A Collection of Misfits
- Jing Hou is awarded the prize "article du mois - Août 2014" SFBBM
April 2014
Congrats again ! Jing Hou won the presentation prize at LMO-11.
Congrats to Jing Hou for her prize of the presentation at Séminaire de Microbiologie de Strasbourg (SMS 2014).
Welcome to Kévin Gérard (DUT génie biologique) and Justine Humbert (M1).
A new publication in collaboration:
The complete genome of Blastobotrys (Arxula) adeninivorans LS3 - a yeast of biotechnological interest.
Biotechnol Biofuels. 2014, 7:66.
February-March 2014
Midterm thesis defense: Jing Hou, "Genetic basis of intraspecific reproductive isolation in yeast", 27th february.
Midterm thesis defense: Anastasie Sigwalt, "Origine génétique de la variation de la tolérance au stress au sein de populations naturelles de levures", 27th mars.
January 2014
Cyrielle Reisser defended her PhD thesis entitled « Analyse de la variabilité intraspécifique chez les levures : résistance à l’ammonium et aux antifongiques azolés » on 31th january.
A photo of the defense here
The team welcomes three new members: Claudia Caradec (IE), Laure Bertsch and Jean-Sébastien Gounot (undergraduate students).
2013
October 2013
2nd participation of the HaploTeam at the Ekiden race in Strasbourg ...and new record 03:34:57... the team almost cathes up with Joseph: 03:30:08 at the marathon !
Just have a look at our new publication 'Genetic basis of the running speed of a freaky population: the HaploTeam 2013'
August 2013
The lab welcomes its newest postdoc, Kelle Freel.
July 2013
New publication in collaboration with the group of Gaël Yvert (ENS - Lyon) and Yoshi Ohya (Tokyo University):
Single-cell phenomics reveals intra-species variation of phenotypic noise in yeast.
BMC Systems Biology 2013, 7:54.
Congratulations to Jackson Peter on his PhD University Fellowship!
April-June 2013
Welcome to new members :
Bai Xueke (M1_statistiques), Elisabetta Punzi (Erasmus), Morand Silber (L3), Virginie Nierat (L3), David Picard-Druet (L3), Christian Brion (Postdoc).
New publication of the team:
Genome-wide analysis of intraspecific transposon diversity in yeast.
BMC Genomics. 2013 Jun 14;14:399.
Mars 2013
New publication of the group:
Genetic basis of ammonium toxicity resistance in a sake strain of yeast: a mendelian case.
G3. 2013, 3(4):733-740.
Nicolas Chevigny (3rd year student) has joined the lab.
January-February 2013
Jackson Peter, Alexandra Vantcheva (master students) and Francis Rousseau-Brochu (Erasmus) have joined the lab. Welcome!
2012 and before
December 2012
France Genomics has selected our project : "The 1002 yeast genomes project: a framework for genome-wide association studies", a collaborative research with the Liti lab.
https://www.france-genomique.org/spip/spip.php?breve5
Cyrielle wins a poster prize at the Health and Life Sciences Doctoral School Day. Congrats!
Denise Stuber joined the lab as a technician.
October 2012
The group run the Ekiden of Strasbourg for the first time
03:40:05... not too bad!
http://connect.garmin.com/activity/237943220
New publication of the group in PLoS ONE:
Comparative mitochondrial genomics within and among yeast species of the Lachancea genus.
PLoS One. 2012, 7(10):e47834.
September 2012
Jing Hou and Anastasie Sigwalt joined the lab as graduate students.
New publication of the group in Genes, Genomes, Genetics (G3):
Mitochondrial genome evolution in a single protoploid yeast species.
G3. 2012, 2(9):1103-11
Sophie Siguenza joined the group as a bioinformatics research scientist.
July 2012
Congratulations to Jing Hou on her PhD University Fellowship!
May-June 2012
The lab has been awarded a NIH R01 Grant for collaborative research with Maitreya Dunham (Washington University, Seattle, USA) and David Hess (University of Santa Clara, Santa Clara, USA).
The lab has been awarded an « Projets Attractivité IDEX 2012 » of the University of Strasbourg.
April 2012
The lab welcomes its newest postdoc, Romain Henry.
February 2012
New publication in collaboration:
Pichia sorbitophila, an interspecies yeast hybrid, reveals early steps of genome resolution after polyploidization.
G3 (Bethesda). 2012, 2(2):299-311.
January 2012
The team has been awarded an ANR Young Investigator Grant.
May 2011
The lab welcomes its newest postdoc, Paul Jung.
October 2010
The lab has been awarded an ANR Program Grant for collaborative research with Gilles Fischer (UPMC, Paris), Bertrand Llorente (CNRS, Marseille) and Cécile Neuveglise (INRA, Grignon).